Incident Response: Exposure Modeling and Dose Response

RHP’s dose response and historic exposure dose reconstruction studies include development of mathematical models which characterize human inhalation exposures; simulation of historic product use and extrapolation of measurements in scenarios not readily measurable; and evaluation of historical workplace, personnel, and regulatory agency records. Novel mathematical models can be validated using RHP’s isolation enclosure which helps clients better understand exposures during application of their products.

RHP has reconstructed historical formulations of building materials through simulation of product use and measurements not readily measurable through use of historical manufacturer formula cards, and resynthesized laboratory scale batches of products for use within an exposure simulation study designed to fill data gaps. In parallel, the RHP can also assist with utilization of regulatory accepted air quality models for accidental releases, to assess community exposures, and to demonstrate compliance with state and federal air quality regulations.